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Year Number of Results
1988 1
1989 1
1990 1
1991 7
1992 17
1993 33
1994 57
1995 68
1996 80
1997 88
1998 90
1999 95
2000 110
2001 96
2002 80
2003 107
2004 77
2005 84
2006 109
2007 76
2008 73
2009 75
2010 86
2011 83
2012 73
2013 81
2014 94
2015 96
2016 81
2017 84
2018 71
2019 80
2020 96
2021 86
2022 77
2023 65
2024 20

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2,391 results

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Page 1
p53 and chemosensitivity in bladder cancer.
Nishiyama H, Watanabe J, Ogawa O. Nishiyama H, et al. Int J Clin Oncol. 2008 Aug;13(4):282-6. doi: 10.1007/s10147-008-0815-x. Epub 2008 Aug 15. Int J Clin Oncol. 2008. PMID: 18704627 Review.
Alterations in p53 represent one of the most common genetic events in patients with invasive urothelial carcinoma and are suggested to be linked to tumor progression, prognosis, and chemosensitivity. p53 possesses various functions, including induction of cell-cycle …
Alterations in p53 represent one of the most common genetic events in patients with invasive urothelial carcinoma and are suggested t …
p53 and retinoblastoma pathways in bladder cancer.
Mitra AP, Birkhahn M, Cote RJ. Mitra AP, et al. World J Urol. 2007 Dec;25(6):563-71. doi: 10.1007/s00345-007-0197-0. Epub 2007 Aug 21. World J Urol. 2007. PMID: 17710407 Review.
A majority of the aggressive, invasive bladder carcinomas have alterations in the p53 and retinoblastoma genes and pathways. Examination of the alterations in the molecules in these pathways that regulate the cell cycle and their effects on the prognosis of bladd …
A majority of the aggressive, invasive bladder carcinomas have alterations in the p53 and retinoblastoma genes and pathways. E …
P53 as a prognostic marker for bladder cancer: a meta-analysis and review.
Malats N, Bustos A, Nascimento CM, Fernandez F, Rivas M, Puente D, Kogevinas M, Real FX. Malats N, et al. Lancet Oncol. 2005 Sep;6(9):678-86. doi: 10.1016/S1470-2045(05)70315-6. Lancet Oncol. 2005. PMID: 16129368 Review.
BACKGROUND: P53 is the most widely investigated molecular marker in bladder cancer. We aimed to review comprehensively the evidence for use of changes in P53 to predict bladder-cancer recurrence, progression, and mortality. ...
BACKGROUND: P53 is the most widely investigated molecular marker in bladder cancer. We aimed to review comprehensively the evi …
Telomerase reverse transcriptase mutation and the p53 pathway in T1 urinary bladder cancer.
Jahnson S, Söderkvist P, Aljabery F, Olsson H. Jahnson S, et al. BJU Int. 2022 May;129(5):601-609. doi: 10.1111/bju.15490. Epub 2021 Jul 4. BJU Int. 2022. PMID: 34028171
OBJECTIVE: To study the telomerase reverse transcriptase (TERT) mutation and the p53 pathway in T1 urinary bladder cancer (UBC). MATERIALS AND METHODS: This prospectively performed population-based study included all patients in the Southeast Healthcare Regio …
OBJECTIVE: To study the telomerase reverse transcriptase (TERT) mutation and the p53 pathway in T1 urinary bladder canc …
An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer.
Lindskrog SV, Prip F, Lamy P, Taber A, Groeneveld CS, Birkenkamp-Demtröder K, Jensen JB, Strandgaard T, Nordentoft I, Christensen E, Sokac M, Birkbak NJ, Maretty L, Hermann GG, Petersen AC, Weyerer V, Grimm MO, Horstmann M, Sjödahl G, Höglund M, Steiniche T, Mogensen K, de Reyniès A, Nawroth R, Jordan B, Lin X, Dragicevic D, Ward DG, Goel A, Hurst CD, Raman JD, Warrick JI, Segersten U, Sikic D, van Kessel KEM, Maurer T, Meeks JJ, DeGraff DJ, Bryan RT, Knowles MA, Simic T, Hartmann A, Zwarthoff EC, Malmström PU, Malats N, Real FX, Dyrskjøt L. Lindskrog SV, et al. Nat Commun. 2021 Apr 16;12(1):2301. doi: 10.1038/s41467-021-22465-w. Nat Commun. 2021. PMID: 33863885 Free PMC article.
The molecular landscape in non-muscle-invasive bladder cancer (NMIBC) is characterized by large biological heterogeneity with variable clinical outcomes. ...Both transcriptome-based subtyping and the level of chromosomal instability provide independent prognostic value bey …
The molecular landscape in non-muscle-invasive bladder cancer (NMIBC) is characterized by large biological heterogeneity with variabl …
The p53 tumor suppressor gene and nuclear protein: basic science review and relevance in the management of bladder cancer.
Smith ND, Rubenstein JN, Eggener SE, Kozlowski JM. Smith ND, et al. J Urol. 2003 Apr;169(4):1219-28. doi: 10.1097/01.ju.0000056085.58221.80. J Urol. 2003. PMID: 12629332 Review.
We outline the basic constitutive functions of p53 and summarize its current role in the management of transitional cell carcinoma of the bladder. ...Nonetheless, randomized prospective studies are needed to determine the potential clinical implications of p53 …
We outline the basic constitutive functions of p53 and summarize its current role in the management of transitional cell carcinoma of …
Role of p53 and Ki-67 immunomarkers in carcinoma of urinary bladder.
Thakur B, Kishore S, Dutta K, Kaushik S, Bhardwaj A. Thakur B, et al. Indian J Pathol Microbiol. 2017 Oct-Dec;60(4):505-509. doi: 10.4103/IJPM.IJPM_246_17. Indian J Pathol Microbiol. 2017. PMID: 29323062
We carried out the present study to demonstrate the clinicohistopathological features and to correlate the p53 and Ki-67 immunoexpression with grade and stage of bladder carcinomas. ...CONCLUSION: Our results corroborate with the opinion that combined use of p53 …
We carried out the present study to demonstrate the clinicohistopathological features and to correlate the p53 and Ki-67 immunoexpres …
P53, CK20, and FGFR3 Overexpression is Associated with the Characteristics of Urothelial Cell Carcinoma of the Bladder.
Asgari M, Firouzi F, Abolhasani M, Bahadoram M, Barahman M, Madjd Z, Mehrazam M, Hassanzadeh S, Akade E. Asgari M, et al. Asian Pac J Cancer Prev. 2023 Sep 1;24(9):3125-3131. doi: 10.31557/APJCP.2023.24.9.3125. Asian Pac J Cancer Prev. 2023. PMID: 37774064 Free PMC article.
OBJECTIVES: The aim of this study was to investigate the association between the overexpression of tumor protein (P53), cytokeratin 20 (CK20), fibroblast growth factor receptor 3 (FGFR3), biomarkers and the grading, prognosis, heterogeneity, and relapse tendency of urothel …
OBJECTIVES: The aim of this study was to investigate the association between the overexpression of tumor protein (P53), cytokeratin 2 …
Tp53 and its potential therapeutic role as a target in bladder cancer.
Ciccarese C, Massari F, Blanca A, Tortora G, Montironi R, Cheng L, Scarpelli M, Raspollini MR, Vau N, Fonseca J, Lopez-Beltran A. Ciccarese C, et al. Expert Opin Ther Targets. 2017 Apr;21(4):401-414. doi: 10.1080/14728222.2017.1297798. Epub 2017 Mar 1. Expert Opin Ther Targets. 2017. PMID: 28281901 Review.
Areas covered: We searched for related publications on Pubmed and ClinicalTrial.gov using the following keywords 'p53, Tp53, p53 and bladder cancer, p53 and therapeutic target'. Relevant articles improved the understanding on p53 pathways and th …
Areas covered: We searched for related publications on Pubmed and ClinicalTrial.gov using the following keywords 'p53, Tp53, p53 …
Alterations of p53 and Rb Pathways Are Associated with High Proliferation in Bladder Urothelial Carcinomas.
Goussia AC, Papoudou-Bai A, Charchanti A, Kitsoulis P, Kanavaros P, Kalef-Ezra J, Stefanou D, Agnantis NJ. Goussia AC, et al. Anticancer Res. 2018 Jul;38(7):3985-3988. doi: 10.21873/anticanres.12685. Anticancer Res. 2018. PMID: 29970521
BACKGROUND/AIM: Since most cancers are associated with alterations of the p53 and Rb pathways, the expression of p53, p21, Rb, p16, p27, cyclin D1, cyclin A, cyclin B1 and Ki67 proteins were analyzed in bladder urothelial carcinomas (BUC). ...Alterations of t …
BACKGROUND/AIM: Since most cancers are associated with alterations of the p53 and Rb pathways, the expression of p53, p21, Rb, …
2,391 results